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Text File  |  1987-10-07  |  830b  |  19 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, AMANTIDINE DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID CNS TOXICITY (PSYCHOSES,
  4.          HALLUCINATIONS, TREMOR, ATAXIA, ETC).
  5.           
  6.          SOME CLINICIANS RECOMMEND THE FOLLOWING MAINTENANCE DOSAGE
  7.          BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.            CREATININE CLEARANCE       MAINTENANCE DOSAGE
  10.                (ML/MINUTE)
  11.           
  12.                 >80                       100mg BID
  13.                 60-79                     200mg/100mg alternate daily
  14.                 40-59                     100mg once daily
  15.                 30-39                     200mg twice weekly
  16.                 20-29                     100mg three times weekly
  17.                 10-19                     200mg/100mg alternate weekly
  18.           
  19.